L-Glutamine – A love story

When it comes to our PSA Performance range of Aminos, one of our most popular purchase by far is L-Glutamine. It’s really not hard to see why, as L-Glutamine is a legend in so many different ways.

If you’ve never heard of L-Glutamine and are looking to learn more, never fear, as we’ve prepared a document that gives you everything you need to know about PSA’s favourite Amino.

A quick definition:

L-glutamine, also known as simply glutamine, is an essential amino acid produced in the human body, and is essential for proper function of the immune system, brain, and digestive system. It is stored in both muscles and blood plasma, and is found mainly in skeletal muscle. It exists in 61% of your skeletal muscle, it also consists of 19% nitrogen, making it the primary transporter of nitrogen into your muscle cells.


L-Glutamine plays an important role in nitrogen balance and protein synthesis in bacteria and small intestine, which is why it is so highly recommended in the health and supplement community as an aid in the following:

  • Curing “Leaky Gut” disorder and healing Ulcers – it acts as a band-aid for your small intestine
  • Improves gastrointestinal health because it is a vital nutrient for the intestines to rebuild and repair
  • Improves IBS and diarrhea by balancing mucus production, which results in healthy bowel movements
  • Colon Cancer – L-Glutamine aids in reducing side effects and increase effectiveness of chemotherapy in those with colon cancer, and may prevent nerve damage caused by breast cancer medications. There are ongoing studies about the effects of L-Glutamine on patients going through Chemotherapy and we will update you with new information about the amino as it develops!

Not only does L-Glutamine help with stomach issues, it is also assists in your fitness and health journey. In terms of development, L-Glutamine:

  • Promotes muscle growth and decreases muscle wasting – Regulates protein synthesis
  • Improves athletic performance recovery from endurance exercise (Note: the impact of L-Glutamine in performance increases with prolonged usage)
  • Improves metabolism and cellular detoxification – it promotes HGH (Human Growth Hormone)
    • Metabolism is accelerated due to increased levels of HGH which allows the more efficient processing of foods and enhancing the efficient metabolism of fats.
    • Cellular Detoxification occurs as Glutamine helps the liver since it cleanses the liver of fatty waste products. Glutamine also helps the liver process toxins more effectively to eliminate toxins in the body, however it is not recommended taking more than the recommended amount per day, as L-Glutamine contains a nitrogen molecule which may tax the liver if taken in large quantities at once (just as taking too much of anything can harm you).
  • Boosts the immune system
  • Blood Sugar Control -it helps prevent hypoglycemia since it is easily converted to glucose when blood sugar is low.
  • Weight Loss & Appetite Suppressant – it is an important metabolic substrate of rapidly proliferating cells.

If you thought there wasn’t enough benefits already, L-Glutamine also aids in brain functions with the following benefits:

  • Mood Improvement
  • Protects the brain from ammonia toxicity
  • Provides energy to the brain
  • Improves mental performance and long-term/short-term memory

In the brain, glutamine is a substrate for the production of both excitatory and inhibitory neurotransmitters (glutamate and gamma-aminobutyric acid, GABA).  Glutamine is also an important source of energy for the nervous system.  If the brain is not receiving enough glucose, it compensates by increasing glutamine metabolism for energy — hence, the popular perception of glutamine as “brain food” and its use as a pick-me-up.

L-Glutamine is becoming an increasingly studied amino as its uses expand over time, we will update you constantly with new information about this supplement as new studies provide insight into this wonderful supplement.